All Publications
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50: Pellman J, Goldstein A, SÅ‚abicki M. Human E3 ubiquitin ligases: accelerators and brakes for SARS-CoV-2 infection. Biochem Soc Trans. 2024 Sep 2:BST20230324. doi: 10.1042/BST20230324. Epub ahead of print. PMID: 39222407.
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49: Li YD, Ma MW, Hassan MM, Hunkeler M, Teng M, Puvar K, Rutter JC, Lumpkin RJ, Sandoval B, Jin CY, Schmoker AM, Ficarro SB, Cheong H, Metivier RJ, Wang MY, Xu S, Byun WS, Groendyke BJ, You I, Sigua LH, Tavares I, Zou C, Tsai JM, Park PMC, Yoon H, Majewski FC, Sperling HT, Marto JA, Qi J, Nowak RP, Donovan KA, SÅ‚abicki M, Gray NS, Fischer ES, Ebert BL. Template-assisted covalent modification underlies activity of covalent molecular glues. Nat Chem Biol. 2024 Jul 29. doi: 10.1038/s41589-024-01668-4. Epub ahead of print. PMID: 39075252.
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47: Park PMC, Park J, Brown J, Hunkeler M, Roy Burman SS, Donovan KA, Yoon H, Nowak RP, SÅ‚abicki M, Ebert BL, Fischer ES. Polymerization of ZBTB transcription factors regulates chromatin occupancy. Mol Cell. 2024 Jul 11;84(13):2511-2524.e8. doi: 10.1016/j.molcel.2024.06.010. PMID: 38996460; PMCID: PMC11305084.
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45: Lane IC, Kembuan G, Carreiro J, Kann MC, Lin W, Bouffard AA, Kreuzer J, Morris R, Schneider EM, Kim JY, Zou C, Salas-Benito D, Gasser JA, Leick MB, SÅ‚abicki M, Haas W, Maus MV, Jan M. Genetic retargeting of E3 ligases to enhance CAR T cell therapy. Cell Chem Biol. 2024 Feb 15;31(2):338-348.e5. doi: 10.1016/j.chembiol.2023.10.024. Epub 2023 Nov 20. PMID: 37989314; PMCID: PMC10922718.
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46: Sarott RC, You I, Li YD, Toenjes ST, Donovan KA, Seo P, Ordonez M, Byun WS, Hassan MM, Wachter F, Chouchani ET, SÅ‚abicki M, Fischer ES, Ebert BL, Hinshaw SM, Gray NS. Chemical Specification of E3 Ubiquitin Ligase Engagement by Cysteine-Reactive Chemistry. J Am Chem Soc. 2023 Oct 11;145(40):21937-21944. doi: 10.1021/jacs.3c06622. Epub 2023 Sep 28. PMID: 37767920.
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45: Kozicka Z, Suchyta DJ, Focht V, Kempf G, Petzold G, Jentzsch M, Zou C, Di Genua C, Donovan KA, Coomar S, Cigler M, Mayor-Ruiz C, Schmid-Burgk JL, Häussinger D, Winter GE, Fischer ES, SÅ‚abicki M, Gillingham D, Ebert BL, Thomä NH. Design principles for cyclin K molecular glue degraders. Nat Chem Biol. 2024 Jan;20(1):93-102. doi: 10.1038/s41589-023-01409-z. Epub 2023 Sep 7. PMID: 37679459; PMCID: PMC10746543.
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44: Miller PG, Sperling AS, Mayerhofer C, McConkey ME, Ellegast JM, Da Silva C, Cohen DN, Wang C, Sharda A, Yan N, Saha S, Schluter C, Schechter I, SÅ‚abicki M, Sandoval B, Kahn J, Boettcher S, Gibson CJ, Scadden DT, Stegmaier K, Bhatt S, Lindsley RC, Ebert BL. PPM1D modulates hematopoietic cell fitness and response to DNA damage and is a therapeutic target in myeloid malignancy. Blood. 2023 Dec 14;142(24):2079-2091. doi: 10.1182/blood.2023020331. PMID: 37595362; PMCID: PMC10733824.
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43: Tsai JM, Aguirre JD, Li YD, Brown J, Focht V, Kater L, Kempf G, Sandoval B, Schmitt S, Rutter JC, Galli P, Sandate CR, Cutler JA, Zou C, Donovan KA, Lumpkin RJ, Cavadini S, Park PMC, Sievers Q, Hatton C, Ener E, Regalado BD, Sperling MT, SÅ‚abicki M, Kim J, Zon R, Zhang Z, Miller PG, Belizaire R, Sperling AS, Fischer ES, Irizarry R, Armstrong SA, Thomä NH, Ebert BL. UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability. Mol Cell. 2023 Aug 3;83(15):2753-2767.e10. doi: 10.1016/j.molcel.2023.06.028. Epub 2023 Jul 20. PMID: 37478846; PMCID: PMC11134608.
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42: Zou C, Yoon H, Park PMC, Patten JJ, Pellman J, Carreiro J, Tsai JM, Li YD, Roy Burman SS, Donovan KA, Gasser J, Sperling AS, Nowak RP, Fischer ES, Davey RA, Ebert BL, SÅ‚abicki M. The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein. iScience. 2023 May 19;26(5):106601. doi: 10.1016/j.isci.2023.106601. Epub 2023 Apr 8. PMID: 37095859; PMCID: PMC10082641.
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41: Li YD, Ma MW, Hassan MM, Hunkeler M, Teng M, Puvar K, Lumpkin R, Sandoval B, Jin CY, Ficarro SB, Wang MY, Xu S, Groendyke BJ, Sigua LH, Tavares I, Zou C, Tsai JM, Park PMC, Yoon H, Majewski FC, Marto JA, Qi J, Nowak RP, Donovan KA, SÅ‚abicki M, Gray NS, Fischer ES, Ebert BL. Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528208. doi: 10.1101/2023.02.14.528208. Update in: Nat Chem Biol. 2024 Jul 29. doi: 10.1038/s41589-024-01668-4. PMID: 36824856; PMCID: PMC9949066.
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40: Boytz R, SÅ‚abicki M, Ramaswamy S, Patten JJ, Zou C, Meng C, Hurst BL, Wang J, Nowak RP, Yang PL, Sattler M, Stone RM, Griffin JD, Gray NS, Gummuluru S, Davey RA, Weisberg E. Anti-SARS-CoV-2 activity of targeted kinase inhibitors: Repurposing clinically available drugs for COVID-19 therapy. J Med Virol. 2023 Jan;95(1):e28157. doi: 10.1002/jmv.28157. Epub 2022 Sep 28. PMID: 36117402; PMCID: PMC9538324.
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39: Koochaki SHJ, SÅ‚abicki M, Lumpkin R, Zou C, Belizaire R, Fischer ES, Ebert BL. A STUB1 ubiquitin ligase/CHIC2 protein complex negatively regulates the IL-3, IL-5, and GM-CSF cytokine receptor common β chain (CSF2RB) protein stability. J Biol Chem. 2022 Oct;298(10):102484. doi: 10.1016/j.jbc.2022.102484. Epub 2022 Sep 13. PMID: 36108743; PMCID: PMC9574515.
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38: SÅ‚abicki M, Sperling AS. Repurposing the repurposed: thalidomide analogs as immune stimulants to overcome T cell exhaustion. Cell Chem Biol. 2022 Aug 18;29(8):1245-1247. doi: 10.1016/j.chembiol.2022.07.004. PMID: 35985276.
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37: Ludwig KU, Schmithausen RM, Li D, Jacobs ML, Hollstein R, Blumenstock K, Liebing J, SÅ‚abicki M, Ben-Shmuel A, Israeli O, Weiss S, Ebert TS, Paran N, Rüdiger W, Wilbring G, Feldman D, Lippke B, Ishorst N, Hochfeld LM, Beins EC, Kaltheuner IH, Schmitz M, Wöhler A, Döhla M, Sib E, Jentzsch M, Moench EC, Borrajo JD, Strecker J, Reinhardt J, Cleary B, Geyer M, Hölzel M, Macrae R, Nöthen MM, Hoffmann P, Exner M, Regev A, Zhang F, Schmid-Burgk JL. Author Correction: LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding. Nat Biotechnol. 2022 Aug;40(8):1295. doi: 10.1038/s41587-022-01428-6. Erratum for: Nat Biotechnol. 2021 Dec;39(12):1556-1562. doi: 10.1038/s41587-021-00966-9. PMID: 35851378; PMCID: PMC9294830.
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36: Sellar RS, Sperling AS, SÅ‚abicki M, Gasser JA, McConkey ME, Donovan KA, Mageed N, Adams DN, Zou C, Miller PG, Dutta RK, Boettcher S, Lin AE, Sandoval B, Quevedo Barrios VA, Kovalcik V, Koeppel J, Henderson EK, Fink EC, Yang L, Chan A, Pokharel SP, Bergstrom EJ, Burt R, Udeshi ND, Carr SA, Fischer ES, Chen CW, Ebert BL. Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells. J Clin Invest. 2022 Aug 15;132(16):e153514. doi: 10.1172/JCI153514. PMID: 35763353; PMCID: PMC9374383.
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35: Nitsch L, Jensen P, Yoon H, Koeppel J, Burman SSR, Fischer ES, Scholl C, Fröhling S, SÅ‚abicki M. BTB-BCL6 dimers as building blocks for reversible drug-induced protein oligomerization. Cell Rep Methods. 2022 Apr 13;2(4):100193. doi: 10.1016/j.crmeth.2022.100193. PMID: 35497498; PMCID: PMC9046236.
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34: Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, SÅ‚abicki M, Frydman J, Jakob U, David DC, Bennett EJ, Bertozzi CR, Sardana R, Eapen VV, Carra S. Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report. Ann N Y Acad Sci. 2022 Apr;1510(1):79-99. doi: 10.1111/nyas.14745. Epub 2022 Jan 8. PMID: 35000205.
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33: Murawska GM, Vogel C, Jan M, Lu X, Schild M, Slabicki M, Zou C, Zhanybekova S, Manojkumar M, Petzold G, Kaiser P, Thomä N, Ebert B, Gillingham D. Repurposing the Damage Repair Protein Methyl Guanine Methyl Transferase as a Ligand Inducible Fusion Degron. ACS Chem Biol. 2022 Jan 21;17(1):24-31. doi: 10.1021/acschembio.1c00771. Epub 2022 Jan 4. PMID: 34982531.
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32: Kim PG, Niroula A, Shkolnik V, McConkey M, Lin AE, SÅ‚abicki M, Kemp JP, Bick A, Gibson CJ, Griffin G, Sekar A, Brooks DJ, Wong WJ, Cohen DN, Uddin MM, Shin WJ, Pirruccello J, Tsai JM, Agrawal M, Kiel DP, Bouxsein ML, Richards JB, Evans DM, Wein MN, Charles JF, Jaiswal S, Natarajan P, Ebert BL. Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis. J Exp Med. 2021 Dec 6;218(12):e20211872. doi: 10.1084/jem.20211872. Epub 2021 Oct 26. PMID: 34698806; PMCID: PMC8552148.
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31: Wilke AC, Doebele C, Zindel A, Lee KS, Rieke SA, Ceribelli M, Comoglio F, Phelan JD, Wang JQ, Pikman Y, Jahn D, Häupl B, Schneider C, Scheich S, Tosto FA, Bohnenberger H, Stauder P, Schnütgen F, Slabicki M, Coulibaly ZA, Wolf S, Bojarczuk K, Chapuy B, Brandts CH, Stroebel P, Lewis CA, Engelke M, Xu X, Kim H, Dang TH, Schmitz R, Hodson DJ, Stegmaier K, Urlaub H, Serve H, Schmitt CA, Kreuz F, Knittel G, Rabinowitz JD, Reinhardt HC, Vander Heiden MG, Thomas C, Staudt LM, Zenz T, Oellerich T. SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. Blood. 2022 Jan 27;139(4):538-553. doi: 10.1182/blood.2021012081. PMID: 34624079; PMCID: PMC8938936.
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30: Huang YH, Chen CW, Sundaramurthy V, SÅ‚abicki M, Hao D, Watson CJ, Tovy A,Reyes JM, Dakhova O, Crovetti BR, Galonska C, Lee M, Brunetti L, Zhou Y, Tatton-Brown K, Huang Y, Cheng X, Meissner A, Valk PJM, Van Maldergem L, Sanders MA, Blundell JR, Li W, Ebert BL, Goodell MA. Systematic Profiling of <i>DNMT3A</i> Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor. Cancer Discov. 2022 Jan;12(1):220-235. doi: 10.1158/2159-8290.CD-21-0560. Epub 2021 Aug 24. PMID: 34429321; PMCID: PMC8758508.
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29: Ludwig KU, Schmithausen RM, Li D, Jacobs ML, Hollstein R, Blumenstock K, Liebing J, SÅ‚abicki M, Ben-Shmuel A, Israeli O, Weiss S, Ebert TS, Paran N, Rüdiger W, Wilbring G, Feldman D, Lippke B, Ishorst N, Hochfeld LM, Beins EC, Kaltheuner IH, Schmitz M, Wöhler A, Döhla M, Sib E, Jentzsch M, Moench EC, Borrajo JD, Strecker J, Reinhardt J, Cleary B, Geyer M, Hölzel M, Macrae R, Nöthen MM, Hoffmann P, Exner M, Regev A, Zhang F, Schmid-Burgk JL. LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding. Nat Biotechnol. 2021 Dec;39(12):1556-1562. doi: 10.1038/s41587-021-00966-9. Epub 2021 Jun 29. Erratum in: Nat Biotechnol. 2022 Aug;40(8):1295. doi: 10.1038/s41587-022-01428-6. PMID: 34188222; PMCID: PMC8678193.
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28: Jan M, Scarfò I, Larson RC, Walker A, Schmidts A, Guirguis AA, Gasser JA, SÅ‚abicki M, Bouffard AA, Castano AP, Kann MC, Cabral ML, Tepper A, Grinshpun DE, Sperling AS, Kyung T, Sievers QL, Birnbaum ME, Maus MV, Ebert BL. Reversible ON- and OFF-switch chimeric antigen receptors controlled by lenalidomide. Sci Transl Med. 2021 Jan 6;13(575):eabb6295. doi: 10.1126/scitranslmed.abb6295. Erratum in: Sci Transl Med. 2022 Apr 13;14(640):eabq3419. doi: 10.1126/scitranslmed.abq3419. Erratum in: Sci Transl Med. 2023 Jul 5;15(703):eadj2197. doi: 10.1126/scitranslmed.adj2197. Erratum in: Sci Transl Med. 2024 Apr 17;16(743):eadp4718. doi: 10.1126/scitranslmed.adp4718. PMID: 33408186; PMCID: PMC8045771.
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27: SÅ‚abicki M, Yoon H, Koeppel J, Nitsch L, Roy Burman SS, Di Genua C, Donovan KA, Sperling AS, Hunkeler M, Tsai JM, Sharma R, Guirguis A, Zou C, Chudasama P, Gasser JA, Miller PG, Scholl C, Fröhling S, Nowak RP, Fischer ES, Ebert BL. Small-molecule-induced polymerization triggers degradation of BCL6. Nature. 2020 Dec;588(7836):164-168. doi: 10.1038/s41586-020-2925-1. Epub 2020 Nov 18. PMID: 33208943; PMCID: PMC7816212.
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26: Jensen P, Carlet M, Schlenk RF, Weber A, Kress J, Brunner I, SÅ‚abicki M, Grill G, Weisemann S, Cheng YY, Jeremias I, Scholl C, Fröhling S. Requirement for LIM kinases in acute myeloid leukemia. Leukemia. 2020 Dec;34(12):3173-3185. doi: 10.1038/s41375-020-0943-5. Epub 2020 Jun 26. PMID: 32591645; PMCID: PMC7612252.
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25: SÅ‚abicki M, Kozicka Z, Petzold G, Li YD, Manojkumar M, Bunker RD, Donovan KA, Sievers QL, Koeppel J, Suchyta D, Sperling AS, Fink EC, Gasser JA, Wang LR, Corsello SM, Sellar RS, Jan M, Gillingham D, Scholl C, Fröhling S, Golub TR, Fischer ES, Thomä NH, Ebert BL. The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K. Nature. 2020 Sep;585(7824):293-297. doi: 10.1038/s41586-020-2374-x. Epub 2020 Jun 3. PMID: 32494016; PMCID: PMC7486275.
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24: Sperling AS, Burgess M, Keshishian H, Gasser JA, Bhatt S, Jan M, SÅ‚abicki M, Sellar RS, Fink EC, Miller PG, Liddicoat BJ, Sievers QL, Sharma R, Adams DN, Olesinski EA, Fulciniti M, Udeshi ND, Kuhn E, Letai A, Munshi NC, Carr SA, Ebert BL. Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs. Blood. 2019 Jul 11;134(2):160-170. doi: 10.1182/blood.2019000789. Epub 2019 May 1. PMID: 31043423; PMCID: PMC6624968.
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23: Hüllein J, SÅ‚abicki M, Rosolowski M, Jethwa A, Habringer S, Tomska K, Kurilov R, Lu J, Scheinost S, Wagener R, Huang Z, Lukas M, Yavorska O, Helfrich H, Scholtysik R, Bonneau K, Tedesco D, Küppers R, Klapper W, Pott C, Stilgenbauer S, Burkhardt B, Löffler M, Trümper LH, Hummel M, Brors B, Zapatka M, Siebert R, Kreuz M, Keller U, Huber W, Zenz T. MDM4 Is Targeted by 1q Gain and Drives Disease in Burkitt Lymphoma. Cancer Res. 2019 Jun 15;79(12):3125-3138. doi: 10.1158/0008-5472.CAN-18-3438. Epub 2019 Apr 18. PMID: 31000522.
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22: Schramm K, Iskar M, Statz B, Jäger N, Haag D, SÅ‚abicki M, Pfister SM, Zapatka M, Gronych J, Jones DTW, Lichter P. DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas. Neuro Oncol. 2019 Jul 11;21(7):867-877. doi: 10.1093/neuonc/noz057. PMID: 30943283; PMCID: PMC6620639.
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21: Trautmann M, Cheng YY, Jensen P, Azoitei N, Brunner I, Hüllein J, Slabicki M, Isfort I, Cyra M, Berthold R, Wardelmann E, Huss S, Altvater B, Rossig C, Hafner S, Simmet T, Ståhlberg A, Åman P, Zenz T, Lange U, Kindler T, Scholl C, Hartmann W, Fröhling S. Requirement for YAP1 signaling in myxoid liposarcoma. EMBO Mol Med. 2019 May;11(5):e9889. doi: 10.15252/emmm.201809889. PMID: 30898787; PMCID: PMC6505681.
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20: Sievers QL, Petzold G, Bunker RD, Renneville A, SÅ‚abicki M, Liddicoat BJ, Abdulrahman W, Mikkelsen T, Ebert BL, Thomä NH. Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN. Science. 2018 Nov 2;362(6414):eaat0572. doi: 10.1126/science.aat0572. PMID: 30385546; PMCID: PMC6326779.
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19: Jethwa A, SÅ‚abicki M, Hüllein J, Jentzsch M, Dalal V, Rabe S, Wagner L, Walther T, Klapper W; MMML Network Project; Bohnenberger H, Rettel M, Lu J, Smits AH, Stein F, Savitski MM, Huber W, Aylon Y, Oren M, Zenz T. TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma. Blood. 2018 Jun 21;131(25):2789-2802. doi: 10.1182/blood-2017-09-806679. Epub 2018 Apr 13. PMID: 29653964.
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18: Dietrich S, OleÅ› M, Lu J, Sellner L, Anders S, Velten B, Wu B, Hüllein J, da Silva Liberio M, Walther T, Wagner L, Rabe S, Ghidelli-Disse S, Bantscheff M, OleÅ› AK, SÅ‚abicki M, Mock A, Oakes CC, Wang S, Oppermann S, Lukas M, Kim V, Sill M, Benner A, Jauch A, Sutton LA, Young E, Rosenquist R, Liu X, Jethwa A, Lee KS, Lewis J, Putzker K, Lutz C, Rossi D, Mokhir A, Oellerich T, Zirlik K, Herling M, Nguyen-Khac F, Plass C, Andersson E, Mustjoki S, von Kalle C, Ho AD, Hensel M, Dürig J, Ringshausen I, Zapatka M, Huber W, Zenz T. Drug-perturbation-based stratification of blood cancer. J Clin Invest. 2018 Jan 2;128(1):427-445. doi: 10.1172/JCI93801. Epub 2017 Dec 11. PMID: 29227286; PMCID: PMC5749541.
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17: Bobrowicz M, Dwojak M, Pyrzynska B, Stachura J, Muchowicz A, Berthel E, Dalla-Venezia N, Kozikowski M, Siernicka M, Miazek N, Zapala P, Domagala A, Bojarczuk K, Malenda A, Barankiewicz J, Graczyk-Jarzynka A, Zagozdzon A, Gabrysiak M, Diaz JJ, Karp M, Lech-Maranda E, Firczuk M, Giannopoulos K, Efremov DG, Laurenti L, Baatout D, Frenzel L, Malinowska A, Slabicki M, Zenz T, Zerrouqi A, Golab J, Winiarska M. HDAC6 inhibition upregulates CD20 levels and increases the efficacy of anti-CD20 monoclonal antibodies. Blood. 2017 Oct 5;130(14):1628-1638. doi: 10.1182/blood-2016-08-736066. Epub 2017 Aug 22. PMID:
28830887. -
16: Wu B, SÅ‚abicki M, Sellner L, Dietrich S, Liu X, Jethwa A, Hüllein J, Walther T, Wagner L, Huang Z, Zapatka M, Zenz T. MED12 mutations and NOTCH signalling in chronic lymphocytic leukaemia. Br J Haematol. 2017 Nov;179(3):421-429. doi: 10.1111/bjh.14869. Epub 2017 Aug 2. PMID: 28771672.
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15: Corso J, Pan KT, Walter R, Doebele C, Mohr S, Bohnenberger H, Ströbel P, Lenz C, Slabicki M, Hüllein J, Comoglio F, Rieger MA, Zenz T, Wienands J, Engelke M, Serve H, Urlaub H, Oellerich T. Elucidation of tonic and activated
B-cell receptor signaling in Burkitt's lymphoma provides insights into regulation of cell survival. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5688-93. doi: 10.1073/pnas.1601053113. Epub 2016 May 6. PMID:27155012; PMCID: PMC4878517. -
14: Dietrich S, Hüllein J, Lee SC, Hutter B, Gonzalez D, Jayne S, Dyer MJ, OleÅ› M, Else M, Liu X, SÅ‚abicki M, Wu B, Troussard X, Dürig J, Andrulis M, Dearden C, von Kalle C, Granzow M, Jauch A, Fröhling S, Huber W, Meggendorfer M, Haferlach T, Ho AD, Richter D, Brors B, Glimm H, Matutes E, Abdel Wahab O, Zenz T. Recurrent CDKN1B (p27) mutations in hairy cell leukemia. Blood. 2015 Aug 20;126(8):1005-8. doi: 10.1182/blood-2015-04-643361. Epub 2015 Jun 11. PMID:
26065650. -
13: Winiarska M, Bojarczuk K, Pyrzynska B, Bil J, Siernicka M, Dwojak M, Bobrowicz M, Miazek N, Zapala P, Zagozdzon A, Krol M, Syta A, Podszywalow-Bartnicka P, Pilch Z, Dabrowska-Iwanicka A, Juszczynski P, Efremov DG, Slabicki M, Zenz T, Le Roy A, Olive D, Rygiel TP, Leusen JH, Golab J. Inhibitors of SRC kinases impair antitumor activity of anti-CD20 monoclonal antibodies. MAbs. 2014;6(5):1300-13. doi: 10.4161/mabs.32106. Epub 2014 Oct 30. PMID: 25517315;
PMCID: PMC4622538. -
12: Goto-Silva L, Maliga Z, Slabicki M, Murillo JR, Junqueira M. Application of shotgun proteomics for discovery-driven protein-protein interaction. Methods Mol Biol. 2014;1156:265-78. doi: 10.1007/978-1-4939-0685-7_18. PMID: 24791995.
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11: SÅ‚abicki M, Zenz T. Improving treatment for chronic lymphocytic leukemia by rational use of monoclonal antibodies. Leuk Lymphoma. 2012 Nov;53(11):2101-2. doi: 10.3109/10428194.2012.720980. Epub 2012 Sep 3. PMID: 22891789.
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10: Krastev DB, Slabicki M, Paszkowski-Rogacz M, Hubner NC, Junqueira M, Shevchenko A, Mann M, Neugebauer KM, Buchholz F. A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. Nat Cell Biol. 2011 Jun 5;13(7):809-18. doi: 10.1038/ncb2264. PMID: 21642980.
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9: SÅ‚abicki M, Theis M, Krastev DB, Samsonov S, Mundwiller E, Junqueira M, Paszkowski-Rogacz M, Teyra J, Heninger AK, Poser I, Prieur F, Truchetto J, Confavreux C, Marelli C, Durr A, Camdessanche JP, Brice A, Shevchenko A, Pisabarro MT, Stevanin G, Buchholz F. A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. PLoS Biol. 2010 Jun 29;8(6):e1000408. doi: 10.1371/journal.pbio.1000408. PMID: 20613862; PMCID: PMC2893954.
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8: Paszkowski-Rogacz M, Slabicki M, Pisabarro MT, Buchholz F. PhenoFam-gene set enrichment analysis through protein structural information. BMC Bioinformatics. 2010 May 17;11:254. doi: 10.1186/1471-2105-11-254. PMID: 20478033; PMCID: PMC2881086.
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7: Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science. 2010 Apr 30;328(5978):593-9. doi: 10.1126/science.1181348. Epub 2010 Apr 1. PMID: 20360068; PMCID: PMC2989461.
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6: Theis M, Slabicki M, Junqueira M, Paszkowski-Rogacz M, Sontheimer J, Kittler R, Heninger AK, Glatter T, Kruusmaa K, Poser I, Hyman AA, Pisabarro MT, Gstaiger M, Aebersold R, Shevchenko A, Buchholz F. Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J. 2009 May 20;28(10):1453-65. doi: 10.1038/emboj.2009.114. Epub 2009 Apr 23. PMID: 19387489; PMCID: PMC2684023.
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5: Ding L, Paszkowski-Rogacz M, Nitzsche A, Slabicki MM, Heninger AK, de Vries I, Kittler R, Junqueira M, Shevchenko A, Schulz H, Hubner N, Doss MX, Sachinidis A, Hescheler J, Iacone R, Anastassiadis K, Stewart AF, Pisabarro MT, Caldarelli A, Poser I, Theis M, Buchholz F. A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell. 2009 May 8;4(5):403-15. doi: 10.1016/j.stem.2009.03.009. Epub 2009 Apr 2. PMID: 19345177.
-
4: Kittler R, Pelletier L, Heninger AK, Slabicki M, Theis M, Miroslaw L, Poser I, Lawo S, Grabner H, Kozak K, Wagner J, Surendranath V, Richter C, Bowen W, Jackson AL, Habermann B, Hyman AA, Buchholz F. Genome-scale RNAi profiling of
cell division in human tissue culture cells. Nat Cell Biol. 2007 Dec;9(12):1401-12. doi: 10.1038/ncb1659. Epub 2007 Nov 11. PMID: 17994010. -
3: Kittler R, Surendranath V, Heninger AK, Slabicki M, Theis M, Putz G, Franke K, Caldarelli A, Grabner H, Kozak K, Wagner J, Rees E, Korn B, Frenzel C, Sachse C, Sönnichsen B, Guo J, Schelter J, Burchard J, Linsley PS, Jackson AL, Habermann B, Buchholz F. Genome-wide resources of endoribonuclease-prepared short interfering RNAs for specific loss-of-function studies. Nat Methods. 2007 Apr;4(4):337-44. doi: 10.1038/nmeth1025. Epub 2007 Mar 11. PMID: 17351622.
-
2: Buchholz F, Kittler R, Slabicki M, Theis M. Enzymatically prepared RNAi libraries. Nat Methods. 2006 Sep;3(9):696-700. doi: 10.1038/nmeth912. PMID:16929314.
-
1: Gorlach S, Slabicki M. Scientists and societies. The Polish biotech gap. Nature. 2004 Feb 26;427(6977):870. doi: 10.1038/nj6977-870b. PMID: 14985771.